Label:
Transformation
Description:
DNA transformation is a naturally occuring but rare event in which DNA can be transferred into bacteria. In 1970, Morton Mandel and Akiko Higa discovered a way to make E. coli more "competent" for transforming foreign DNA. Their calcium chloride method is widely used today to obtain high-efficiency transforming cells.
Biological elements:
E. coli, calcium chloride
Concepts precesses:
transforming cells
Tools & methods :
calcium chloride